What is the primary benefit of using long-acting nitrates in patients with angina?

The primary benefit of using long-acting nitrates in patients with angina is to decrease the frequency of angina episodes. Long-acting nitrates work by providing a sustained dilation of blood vessels, which improves blood flow to the heart muscle and reduces the myocardial oxygen demand. This helps to alleviate the symptoms of angina pectoris, which is characterized by chest pain or discomfort due to reduced blood flow to the heart.

By reducing the frequency with which patients experience angina episodes, long-acting nitrates can significantly enhance the quality of life for individuals suffering from this condition. Patients often find that they can participate in daily activities with less discomfort and anxiety about having an angina attack.

While nitrates may contribute to improved exercise tolerance and can have positive impacts on cardiovascular health, the most direct and important outcome of their use is the reduction in the occurrence of angina episodes. This targeted effect makes long-acting nitrates a crucial element in the management of angina.