Which of the following medications is commonly used as a first line treatment for chronic stable angina?

Beta-blockers are commonly used as a first-line treatment for chronic stable angina due to their ability to reduce myocardial oxygen demand. They work by blocking the effects of adrenaline on the heart, leading to a decrease in heart rate and contractility. This reduction in workload allows the heart to function more efficiently and can help alleviate the chest pain associated with angina.

In the context of chronic stable angina, the main goal is to improve the patient's quality of life and prevent angina episodes. Beta-blockers have proven efficacy in both reducing the frequency of angina attacks and improving exercise tolerance.

While antiplatelet agents, ACE inhibitors, and nitroglycerin may have roles in the management of angina, they do not serve as the initial standard treatment for chronic stable angina. Antiplatelet agents are primarily used to prevent thrombotic events and manage cardiovascular risks. ACE inhibitors can provide benefits in patients with certain coexisting conditions like heart failure or hypertension but are not specifically first-line for angina. Nitroglycerin, although effective for immediate relief of angina attacks, is typically used on an as-needed basis rather than as a maintenance therapy.